THE ROLE OF AEROBIC AND ANAEROBIC MICROFLORA IN CLINICAL BEHAVIOR OF DENTAL MUKOSITIS AND PERIIMPLANTITIS

Gudaryan А. А.

CONTENTS

Scentific article

Objective: to set the role of staphylococcus, mycotic and anaerobic infection in the genesis of in-flammatory complications in the deferred period after dental implantation and to develop new methodological ap-proaches on their suppression. Materials and methods. The inspection of 32 patients with inflammatory complications is conducted in long date after intraosseous dental implantationt: at 18 patints – dental mucositis were diagnosed and at 14 patiens – dental peri-implantitis І-ІІ degrees. Among them there were 17 (53,1%) men and 15 (46,9%) women, in age from 34 to 52 years. For determination of qualitative composition of bacterial agents of peri-implant area used the method of classic bacteriologic examination, and also expressmethod of polymerase chain reaction (PCR) with subsequent reverse DNK by hybridization. Results. Тhe article presents results of studying the role of aerobic and anaerobic microflora in the development of mucositis and dental pereimplantitis in 32 patients in the later periods after intraosseous dental implantation. The purpose of the study is – to establish the role of staph of fungal and anaerobic infections in the occurrence of infectious complications in the delayed period after the dental implantation and to develop new methodological ap-proaches to address them. Conducted bacteriological studies revealed that dental mucositis and peri-implantitis are characterized by differences in the etiological structure. So, in the material taken from patients with peri-implant mucositis often identified aerobic microflora (in 88. 9%) and association with anaerobes (11.1% of cases). The wide spectrum of aerodes is presented in order of decrease of the followings bacteria: Streptococcus intermedius (94,4%), Peptostreptococcus micros (77,8%), Staphylococcus spp. (44,4%), Enterobacter spp. (16,7%), Aci-netobacter spp. (11,1%). Anaerobic bacteria at patients with dental mucositis manifest itself rarely (in 16,7%). In one case of dental mucositis there were paradontopatogenic microorganisms in a peri-implant area: Bacteroides forsythus, A. Actinomycetemcomitans and Porphyromonas gingivalis. While, as in the material taken from the peri-implant pocket in patients with dental peri-implantitis, revealed the mix – infection characterized by a large variety of anaerobes (63. 3%) and gram-negative aerobic flora (in 36.7% of cases). Multiinfection was presented the followings paradontopatogenic microorganisms: Bacteroides forsythus (in 55,6% cases), Porphyromonas gingivalis (50,0%), Fusobacterium nucleatum (44,4%), A. Actinomycetemcomitans (38,9%), Prevotella intermedia (38,9%). Their association with the mushrooms of sort of Candida spp., Enterobacter spp., Streptococcus intermedius, Peptostreptococcus micros and Staphylococcus aureus is exposed accordingly in 44,4%, 38,9%, 13,2%, 13,2% and 28,5% cases. Thus on the basis of laboratory data in the treatment of peri-implant mucositis and peri-implantitis is necessary to use a course appointment of differentiated, directed antibiotic therapy.

periimplantitis, mucositis, dental implantation

• Esposito M. Treatment of periimplantitis: what interventions are effective? A Cochrane systematic review / M. Esposito, M. G. Grusovin, H. V. Worthington // Oral Implantol. – 2012. – № 5. – P. 21-41.
• Koyanagi T. Comprehensive microbiological findings in periimplantitis and periodontitis / T. Koyanagi, M. Sakamoto, Y. Takeuchi1, N. Maruyama // J. Clinical Periodontology. – 2013. – № 40. – P. 218-226.
• Mesmer C. Clinical, microbiological and immunological findings in peri-implantitis patients with bar-retained lower removable partial dentures, compared to a healthy control group (12-month-follow-up) / C. Mesmer, A. Forster, M. Antal, K. Nagy // Fogorv. Sz. – 2012. – № 105. – P. 59-64.
• Vered Y. Teeth and implant surroundings: Clinical health indices and microbiologic parameters / Y. Vered, A. Zini, J. Mann // J. Quintessence International. – 2011. – № 42. – P. 339-344.

«Bulletin of problems biology and medicine» Issue 2 part 1 (107), 2014 year, 132-135 pages, index UDK 616.314-089.843-002-092-037:616.71-007.234