METHOD OF DETERMINING INDICATORS CONNECTION OF THE STATE OF PERIODONTAL INFLAMMATION AND ORAL MICROBIOTA
About the author:
Zaitsev A. V., Boychenko O. M., Kotelevska N. V., Nikolishin A. K.
Heading:
METHODS AND METHODOLOGIES
Type of article:
Scentific article
Annotation:
At present, it is believed that the cause of the development of inflammatory periodontal diseases is the influence of the microbial content of dental plaque on the tissue and the local tissue response to it. The intensity of the local tissue response varies depending on the manifestation of local pathophysiological reactions in response to damage and the involvement of systemic body reactions. To assess the state of the periodontal status before and after the treatment, various indicators characterizing the state of the periodontal tissues are used. This includes various indices – gingival and periodontal: PMA (modified by Parma, 1960), gingival index according to Silness-Loe (1964), periodontal index (according to Russel, 1956), SPITN index, etc. The above PMA index (papillary-marginalalveolar), proposed by Masser and modified by Parma in 1960 p., is used to assess the inflammatory process in the gums, that is, the state of the pathophysiological reaction in them. Assessment of the state of oral hygiene is carried out using hygienic indices – hygienic index according to Fedorov-Volodkina (1970), hygienic index according to Green-Vermillion (OHI-S), etc. The OHI-S simplified oral hygiene index is used to detect dental plaque and calculus, i.e., the organization of dental biofilm. But it is sometimes difficult for a specialist to find his way in the formation of a treatment strategy due to an inadequate interpretation of the compatibility of the indicated indicators. In such cases, mathematical methods should be used for help. The purpose of the study was to create a methodology that provides insight into the compatibility and assessment of indicators of the state of the human oral microbiome and the body’s response to it. The materials were data from studies that characterize representatives of oral microbiocenosis and the manifestation of local pathophysiological reactions in response to this. As a method, mathematical analysis was chosen, in particular, it is an approximation, which is carried out using the Excel 2010 computer program. The used method of determining the compatibility and assessment of indicators of the state of the human oral microbiome and the body’s reaction to it allows us to make assumptions about the correlation of these components. The graphic display gives a good idea of deviations from the state of remission. The dependences obtained by the computer program refer to quadratic functions that can be differentiated and integrated in all domains of definition. And also to find the points of extremums, derivatives and primitives. This makes it possible to further consider the above-mentioned dependencies by means of mathematical analysis.
Tags:
microbiota,periodontium,mathematical analysis
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Publication of the article:
«Bulletin of problems biology and medicine» Issue 1 (168), 2023 year, 270-275 pages, index UDK 616.314-002-06-07