MODERN METHODS OF PREVENTION AND TREATMENT OF HEAD AND NECK PATHOLOGICAL SCARS

Ohonovskyi R. Z., Pohranychna H. R., Lutsenko N. S., Loza H. O., Nahirnyi Y. P.

METHODS AND METHODOLOGIES

Scentific article

As is well known, traumatic, surgical and burn wounds or wounds caused by infectious agents can turn into pathological scars. Some authors believe that scars appear only due to atypical wound healing, which changes the level of collagen in the dermis. A scar (Cicatrix) is a secondary morphological element of the skin that is formed when it is damaged, and especially when the reticular dermis is damaged. Thus, a scar is formed for about 12 months, during which important processes in wound healing and the formation of a future scar take place. The purpose of the study: to highlight and analyze data on modern methods of prevention and treatment of pathological scars of the head and neck. One of the modern methods of preventing pathological scars is PRP (Platelet-rich plasma) injections. This is a new and modern method of prevention and treatment, which is constantly expanding, and shows great prospects in medicine. The combined use of PRP with laser therapy and microneedling is becoming an increasingly popular procedure in aesthetic dermatology every year. Emer J describes in his studies that PRP combined with hardware treatment reduces transepidermal water loss and reduces inflammatory hyperpigmentation. Thus, one of the recommendations for the prevention and treatment of pathological scars is silicone materials. These are polymers with a silicone-oxygen or siloxane base with additional methyl groups that form polydimethylsiloxane links. Wu W and the authors using hypoallergenic microporous tape in their clinical studies proved that it is able to reduce tension in tissues. Limmer EE and the authors used a painless alternative to corticosteroid injections in their studies, namely corticosteroid tape. Correctly chosen method of prevention and treatment contributes to a better result, which in turn reduces the time of wound healing, reduces the probability of the formation of pathological scars of the head and neck, and reduces the percentage of recurrences in the postoperative period, which is a desirable result not only for doctors, but also for patients .

head and neck,maxillofacial area,wounds,prevention of the formation of pathological scars

1. Monstrey S, Middelkoop E, Vranckx JJ, Bassetto F, Ziegler UE, Meaume S, Téot L. Updated scar management practical guidelines: non- invasive and invasive J Plast Reconstr Aesthet Surg. 2014;67(8):1017-25. DOI: 10.1016/j.bjps.2014.04.011.
2. Toropov OA, Avetikov DS, Lokes KP, Steblovskyi DV, Skrypnyk VM, Prykhidko RA. Vykorystannia kriokonservovanoi platsenty dlia profilaktyky utvorennia patolohichnykh rubtsiv holovy y shyi na intra- i pisliaoperatsiinomu etapakh pry planovykh operatyvnykh vtruchanniakh (Ohliad literatury). Ukrainskyi stomatolohichnyi 2020;2:74-80. DOI: 10.31718/2409-0255.2.2020.12.
3. Huang C, Liu L, You Z, Wu Z, Du Y, Ogawa Clinical and Pathological Diagnosis of Scars. In: Ogawa R. (eds). Total Scar Management. Springer: Singapore; 2020. 184 p.
4. Deng X, Gould M, Ali MA. A review of current advancements for wound healing: Biomaterial applications and medical devices. J Biomed Mater Res B Appl 2022 Nov;110(11):2542-2573. DOI: 10.1002/jbm.b. 35086.
5. Kolimi P, Narala S, Nyavanandi D, Youssef AAA, Dudhipala N. Innovative Treatment Strategies to Accelerate Wound Healing: Trajectory and Recent Cells. 2022 Aug 6;11(15):2439. DOI: 10.3390/cells111 52439.
6. Kang RS, Lee MK, Seth R, Keller Platelet-Rich Plasma in Cosmetic Surgery. Int J Otorhinolaryngol Clin. 2013;5(1):24-28.
7. Sand JP, Nabili V, Kochhar A, Rawnsley J, Keller G. Platelet-Rich Plasma for the Aesthetic Surgeon. Facial Plast Surg. 2017;33(4):437- DOI: 10.1055/s-0037-1604240.
8. Zhu JT, Xuan M, Zhang YN, Liu HW, Cai JH, Wu YH, et The efficacy of autologous platelet-rich plasma combined with erbium fractional laser therapy for facial acne scars or acne. Mol Med Rep. 2013;8(1):233-7. DOI: 10.3892/mmr.2013.1455.
9. Gawdat HI, Hegazy RA, Fawzy MM, Fathy M. Autologous platelet rich plasma: topical versus intradermal after fractional ablative carbon dioxide laser treatment of atrophic acne Dermatol Surg. 2014;40(2):152-161. DOI: 10.1111/dsu.12392.
10. Emer Platelet-Rich Plasma (PRP): Current Applications in Dermatology. Skin Therapy Lett. 2019;24(5):1-6.
11. Hassanpour SE, Farnoush N, Karami MY, Makarem The effect of silicone gel versus contractubex gel on the upper-extremity postsurgical scars: A randomized, double-blinded, controlled trial. Med J Islam Repub Iran. 2020;34:146. DOI: 10.34171/mjiri.34.146.
12. Yang S, Luo YJ, Luo C. Network Meta-Analysis of Different Clinical Commonly Used Drugs for the Treatment of Hypertrophic Scar and Front Med (Lausanne). 2021;8:691628. DOI: 10.3389/fmed.2021.691628.
13. Owji N, Khalili MR, Khademi B, Shirvani M, Sadati Comparison of the Effectiveness of Onion Extract, Topical Steroid, and Petrolatum Emollient in Cosmetic Appearance of Upper Blepharoplasty Scar. J Curr Ophthalmol. 2020;32(4):408-413. DOI: 10.4103/JOCO. JOCO_39_20.
14. Wu W, Zhao Y, Chen Y, Zhong Comparing the Efficacy of Multiple Drugs Injection for the Treatment of Hypertrophic Scars and Keloid: A Network Meta-Analysis. Aesthetic Plast Surg. 2022. DOI: 10.1007/s00266-022-03163-4.
15. Limmer EE, Glass DA A Review of Current Keloid Management: Mainstay Monotherapies and Emerging Approaches. Dermatol Ther (Heidelb). 2020;10(5):931-948. DOI: 10.1007/s13555-020-00427-2.
16. Barone N, Safran T, Vorstenbosch J, Davison PG, Cugno S, Murphy Current Advances in Hypertrophic Scar and Keloid Management. Semin Plast Surg. 2021;35(3):145-152. DOI: 10.1055/s-0041-1731461.
17. Mehta S, Coffey R, Jones LM, Powell HM, Bailey Survey of national and local practice of compression therapy timing for burn patients in the United States. Burns. 2019;45(5):1215-1222. DOI: 10.1016/j.burns.2018. 12.016.
18. Tosa M, Ogawa Photodynamic therapy for keloids and hypertrophic scars: a review. Scars Burn Heal. 2020;6:2059513120932059. DOI: 10.1177/2059513120932059.
19. Hultman CS, Friedstat JS, Edkins RE, Cairns BA, Meyer Laser resurfacing and remodeling of hypertrophic burn scars: the results of a large, prospective, before-after cohort study, with long-term follow-up. Ann Surg. 2014;260:519-532.
20. Field Massage therapy research review. Complement Ther Clin Pract. 2016;24:19-31. DOI: 10.1016/j.ctcp.2016.04.005.

«Bulletin of problems biology and medicine» Issue 1 (168), 2023 year, 276-279 pages, index UDK 617.51./.53-001.43-003.92

10.29254/2077-4214-2023-1-168-276-279