STRUCTURAL ORGANIZATION OF RATS ADRENAL GLANDS IN NORMAL STATE

Donchenko S. V., Bilash S. M.

MORPHOLOGY

Scentific article

This work contains a study of the structure of the adrenal glands of rats in normal conditions and their comparison with the adrenal glands of humans, which can be used in further research. For this experiment, we used a biopsy of rat adrenal glands. The resulting sections were stained with hematoxylin, eosin, methylene blue, and toluidine blue. During our research, we used: histological, morphometric, and statistical methods. As a result of this study, it was established that the adrenal glands consist of a capsule, cortex, and medulla. The cortical substance, in turn, was divided into three morphologically different zones: glomerular, fascicular, and reticular. The cells of the glomerular zone are polygonal in shape and small in size; the cells of the fascicular zone are placed in parallel rows, have large sizes, and form bundles; the cells of the reticular zone have a rounded shape and form multidirectional bundles resembling a grid. The medulla is separated from the cortex substance by a layer of connective tissue. The medulla cells are formed by chromaffinocytes, among which epinephrocytes and norepinephocytes were identified. After establishing the sizes of the component adrenal glands, we obtained the following data: the average total thickness of the capsule was (33.52±0.21) μm; the average thickness of the cortical substance was (583.31±1.42) μm; the average total thickness of the glomerular zone – (44.27±0.21) μm; the average total thickness of the fasciculate zone was (401.87±2.68) μm; the average total thickness of the reticular zone was (131.56±0.86) μm. The average total thickness of the medulla is (382.22±3.61) μm. We can use the obtained data to interpret the obtained results for a person during research and experiments, as well as in the future, to study the effect of a complex of food additives on the morphofunctional state of the adrenal glands

adrenal glands,nutritional supplements,cortex,medulla,monosodium glutamate,sodium nitrite,Ponceau 4R.

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«Bulletin of problems biology and medicine» Issue 4 (167), 2022 year, 291-295 pages, index UDK 611.451-024

10.29254/2077-4214-2022-4-167-291-295