ОРАЛЬНЫЙ МИКРОБИОМ И ВОЗРАСТ

Островская С. С., Герасимчук П. Г.

ОБЗОРЫ ЛИТЕРАТУРЫ

Научная статья.

Приведены данные о возрастных факторах риска развития нейродегенеративных заболеваний, в том числе болезни Альцгеймера, связанные с оральной микробиотой. Длительное воздействие циркулирующих провоспалительных цитокинов, таких как TNFα и IL1β, способствует нарушению гематоэнцефалического барьера, позволяя измененной с возрастом оральной микробиоте проникать в мозг через обильные иннервации ротовой полости, способствуя развитию тяжелой патологии. Знание того, как процесс старения и воспаление воздействуют на оральный микробиом пожилых людей, открывает новые возможности значительно улучшить их общее состояние.

оральный микробиом, старение, болезнь Альцгеймера

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«Вестник проблем биологии и медицины» Выпуск 2 (144), 2018 год, 40-43 страницы, код УДК 612.31:616-008.87-93:613.9-053

10.29254/2077-4214-2018-2-144-40-43