ПРЕНАТАЛЬНОЕ И ПОСТНАТАЛЬНОЕ ВОЗДЕЙСТВИЕ СВИНЦА (ОБЗОР ЛИТЕРАТУРЫ)

Островская С. С.

ОБЗОРЫ ЛИТЕРАТУРЫ

Научная статья.

В обзоре показано, что влияние свинца увеличивает вероятность внутриутробной гибели плода, рождения дефективного или нежизнеспособного ребенка, имеет долгосрочные последствия, является причиной многих заболеваний у взрослого организма. Перечисленные факты указывают на необходимость контроля уровня свинца в крови матери и достаточного потребления при беременности витаминных добавок, содержащих, в том числе, железо и кальций, что помогает сохранить здоровье детей в современной экологической обстановке.

свинец, пренатальное и постнатальное воздействие

1. Allen K.A. Is Prenatal Lead Exposure a Concern in Infancy? What Is the Evidence? / K.A. Allen // Adv. Neonatal. Care. – 2015. – V.15. – № 6. – P. 416-420.
2. Association of cord blood levels of lead, arsenic, and zinc and home environment with children neurodevelopment at 36 months living in Chitwan Valley, Nepal / R. P. Parajuli, M. Umezaki, T. Fujiwara [et. al.] // PLoS One. – 2015. – V. 10. – № 3. — e0120992.
3. Adverse effects of maternal lead levels on birth outcomes in the ALSPAC study: a prospective birth cohort study / C. M. Taylor, J. Golding, A. M. Emond // BJOG. – 2015. – V. 122. – № 3. – P. 322–328.
4. Barkur R.R. Assessment of oxidative stress in hippocampus, cerebellum and frontal cortex in rat pups exposed to lead (Pb) during specific periods of initial brain development / R.R. Barkur, L.K. Bairy // Biol. Trace. Elem. Res. – 2015. – V. 164. – № 2. – P. 212-218.
5. Breast milk lead and cadmium levels in suburban areas of Nanjing, China / K.S. Liu, J.H. Hao, Y.Q. Xu [et al.] // Chin. Med. Sci. J. – 2013. – V. 28. – № 1. – P. 7-15.
6. Clemow Y.H. Effects of Pb plus Cd mixtures on toxicity, and internal electrolyte and osmotic balance in the rainbow trout (Oncorhynchus mykiss) / Y.H. Clemow, M.P. Wilkie // Aquat. Toxicol. – 2015. – V. 161. P. 176-188.
7. Environmental Lead (Pb) Exposure Versus Fatty Acid Content in Blood and Milk of the Mother and in the Blood of Newborn Children / I. Baranowska-Bosiacka, I. Kosińska, D. Jamioł [et al.] // Biol. Trace. Elem. Res. – 2016. – V. 170. – P. 279-287.
8. Effects of lead (Pb) exposure during gestation and lactation on female pubertal development in the rat / R.K. Dearth, J.K. Hiney, V. Srivastava [et al.] // Reprod. Toxicol. – 2002. – V. 16. – № 4. – P. 343-352.
9. Effect of maternal bone lead on length and head circumference of newborns and 1-month-old infants / M. Hemández-Avila, K.E. Peterson, T. Gonzalez-Cossío [et al.] // Arch. Environ. Health. – 2002. – V. 57. № 5. – P. 482-488.
10. Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneurons and subcortical dopamine system hyperactivity presentin schizophrenia / K.H. Stansfield, K.N. Ruby, B.D. Soares [et al.] // Transl. Psychiatry. – 2015. – V.5. — № 3. – Р. 522.
11. Gundacker C. The role of the placenta in fetal exposure to heavy metals / C. Gundacker, M. Hengstschläger // Wien. Med. Wochenschr. – 2012. – V. 162. – № (9-10). – P. 201-206.
12. Jakubowski M. Development of a Coherent Approach to Human Biomonitoring in Europe. Coordination Action Priority 8.1. D 6.1 – 6.3 Utility and Sensitivity of Biomarkers. 2006 / M. Jakubowski. — Available: http: // www.euhumanbiomonito-ring.org/doc/esbio_ wp6.1_6.3.pdf [accessed 20 August 2012.
13. Jain R.B. Effect of pregnancy on the levels of blood cadmium, lead and mercury for females aged 17-39 years old / R.B. Jain // J. Toxicol. Environ. Health A. – 2013. – V. 76. – № 1. – P. 58-69.
14. Lead in the placenta, membranes, and umbilical cord in relation to pregnancy outcome in a lead-smelter community / P.A. Baghurst, E.F. Robertson, R.K. Oldfield [et al.] // Environ. Health. Perspect. – 1991. – V. 90. – P. 315-320.
15. Lead exposure induces changes in 5-hydroxymethylcytosine clusters in CpG islands in human embryonic stem cellsand umbilical cord blood / A. Sen, P. Cingolani, M.C. Senut [et al.] // Epigenetics. – 2015. – V. 10. – № 7. – Р. 607-621.
16. Maternal lead exposure and risk of congenital heart defects occurrence in offspring / Z. Liu, Y. Yu, X. Li [et al.] // Reprod. Toxicol.– 2015. – V. 51. – P. 16.
17. Molecular determinants of Pb2+ interaction with NMDA receptor channels / P. Gavazzo, I. Zanardi, I. Baranowska-Bosiacka [et al.] // Neurochem. Int. – 2008. – V. 52. – № (1-2). – P. 329-337.
18. Mercury, Cadmium, and Lead Levels in Human Placenta: A Systematic Review / M.D. Esteban-Vasallo, N. Aragonés, M. Pollan [et al.] // Environ. Health. Perspect. – 2012. – V. 120. – № 10. – P. 1369-1377.
19. Neurodeveloment in Early Childhood Affected by Prenatal Lead Exposure and Iron Intake / S. Shah-Kulkarni, M. Ha, B.M. Kim [et al.] // Medicine (Baltimore). – 2016. – V. 95. – № 4. – Р. 2508.
20. Partition of environmental chemicals between maternal and fetal blood and tissues / L.L. Needham, P. Grandjean, B. Heinzow [et al.] // Environ. Sci. Technol. – 2011. – V. 45. – P. 1121-1126.
21. Prenatal lead exposure and weight of 0- to 5-year-old children in Mexico city / M. Afeiche, K.E. Peterson, B.N. Sánchez [et al.] // Environ. Health Perspect. – 2011. – V. 119. – № 10. – P. 1436-1441.
22. Perinatal exposure to lead induces morphological, ultrastructural and molecular alterations in the hippocampus / I. Baranowska-Bosiacka, L. Strużyńska, I. Gutowska [et al.] // Toxicology. – 2013. – V. 303. – P. 187-200.
23. Prenatal lead and cadmium co-exposure and infant neurodevelopment at 6 months of age: the Mothers and Children’s Environmental Health (MOCEH) study / Y. Kim, E.H. Ha, H. Park [et al.] // Neurotoxicology. – 2013. – V. 35. – P. 15-22.
24. Prenatal exposure to lead in relation to risk of preterm low birth weight: A matched case-control study in China / B. Zhang, W. Li, Y. Xia [et al.] // Reprod. Toxicol. – 2015. – V. 57. – P. 190-195.
25. Postnatal growth following prenatal lead exposure and calcium intake / Y.C. Hong, S.S. Rulkarni, Y.H. Lim [et al.] // Pediatrics. – 2014. – V. 134. – № 6. – P. 1151-1159.
26. Quality control and statistical modeling for environmental epigenetics: a study on in utero lead exposure and DNA methylation at birth / J.M. Goodrich, B.N. Sánchez, D.C. Dolinoy [et al.] // Epigenetics. – 2015. – V. 10. – P. 19-30.
27. Snyder M.A. NMDA hypofunction as a convergence point for progression and symptoms of schizophrenia / M.A. Snyder, W.J. Gao // Front. Cell. Neurosci. – 2013. – V. 7. – P. 31-50.
28. Sex-dependent effects of lead and prenatal stress on post-translational hitone modifications in frontal cortex and hippocampus in the early postnatal brain / J.S. Schneider, D.W. Anderson, S.K. Kidd [et al.] // Neurotoxicology. – 2016. – V. 24. – № 54. – P. 65-71.
29. Sex-dependent impacts of low-level lead exposure and prenatal stress on impusive choice behavior and associated biochemical and neurochemiсal мani-festations / H.I. Weston, D.D. Weston, J.L. Allen [et al.] // Neurotoxicology. 2014. – V. 44. P. 169183.
30. Sanders A.P. Perinatal and Childhood Exposure to Cadmium, Manganese, and Metal Mixtures and Effects on Cognition and Behavior: A Review of Recent Literature / A.P. Sanders, H.B. Claus, R.O. Wright // Curr. Environ. Health. Rep. 2015. V. 2. № 3. P. 28422894.
31. Tobaco smoke exposure during pregnancy increases maternal blood lead levels affecting neonate birth weight / M. Chelchowska, J. Ambroszkiewicz, K. Jablonka-salach [et al.] // Biol. Trace. Elem. Res. 2013. – V. 155. – P. 169-175.
32. Tekin D. The effects of metallothionein 2A polymorphism on lead metabolism: are pregnant women with a heterozygote genotype for metallothionein 2A polymorphism and their newborns at risk of having higher blood lead levels? / D. Tekin, Z. Kayaalti, T. Söylemezoglu // Int. Arch. Occup. Environ. Health. – 2011. – V. 85. – P. 631-637.
33. Windows of lead exposure sensitivity, attained height, and body mass index at 48 months / M. Afeiche, K.E. Peterson, B.N. Sánchez [et al.] // J. Pediatr. – 2012. – V. 160. – № 6. – P. 1044-1049.
34. WHO, http://www.who.int/ipcs/features/lead.pdf.Access. 18 November 2013.

«Вестник проблем биологии и медицины» Выпуск 4 Том 1 (133), 2016 год, 52-56 страницы, код УДК 618.29:612.65:661.852