Орлова Ю. А.

К ВОПРОСУ ПАТОГЕНЕЗА НЕКОТОРЫХ ПРОВОСПАЛИТЕЛЬНЫХ И ИММУНОЛОГИЧЕСКИХ ЗВЕНЬЕВ ЭНДОМЕТРИОИДНОЙ БОЛЕЗНИ


Об авторе:

Орлова Ю. А.

Рубрика:

ОБЗОРЫ ЛИТЕРАТУРЫ

Тип статьи:

Научная статья.

Аннотация:

В представленном аналитическом обзоре литературы подана информация о распространенной гинекологической патологии – эндометриоидной болезни. Актуальность данной проблемы представляется значимой в связи с увеличением распространенности среди женщин всех возрастов, ухудшением качества их жизни и ограничением репродуктивного потенциала. Цель обзора литературы – это изучение последних данных о патогенетических звеньях хронического воспаления и нарушений в иммунной системе у женщин с эндометриозом. Считается, что эндометриоз – это болезнь макрофагов. Активные вещества, продуцируемые этими клетками вызывают целый каскад воспалительных реакций. На сегодняшний день остается много нерешенных вопросов в аспекте инициирования и поддержания патологической цепи воспалительной реакции у женщин с указанной болезнью. В частности роли типа поляризации макрофагов и CSF–1 в данных процессах. Поэтому дальнейшее изучение дискутабельных вопросов в генезе эндометриоза представляется полезным для внедрения новых диагностических и лечебных тактик.

Ключевые слова:

эндометриоз, макрофаги, аденомиоз, бесплодие, болевой синдром

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Публикация статьи:

«Вестник проблем биологии и медицины» Выпуск 4 том 1 (153), 2019 год, 38-43 страницы, код УДК 618.14-002:612.017

DOI: