TOPOLOGICAL CHARACTERISTIC OF THE INTERSTITIAL SPACE IN THE LOBULE OF PANCREAS IN THE AGE ASPECT

Pelipenko L. B., Yeroshenko G. A., Lisachenko O. D.

MORPHOLOGY

Scentific article

Due to the development of clinical anatomy and gastroenterology, the interest of morphological scientists to a detailed study of the digestive system, in particular, the pancreas as a complex morpho-functional system, is growing. Diagnosis of pancreatic diseases is one of the most difficult problems in gastroenterology, but achieving the desired result in the treatment of people suffering from pancreatic diseases, directly depends on the account of structural and functional indicators of the norm, without knowledge of which it is impossible to make a clear idea of the nature of a pathological process . The aim of the research was to study the structure and correlation of the components that make up the individual lobule of pancreatic gland of a newborn and an adult human. The material of the study was 10 fragments of pancreatic preparations of newborns and 10 fragments of pancreatic preparations of mature people of 1 period (aged from 22 to 35 years), who died from causes not related to diseases of the gastrointestinal tract and who didn’t have them in the anamnesis. The material was fixed in a 4% solution of glutaraldehyde and sealed in ЭПОН -812 according to the generally accepted procedure. Serial semi-thin sections were obtained on the ultramicrotome of УМТП -7, 0.1 solution of toluidine blue was used as a dye. Histological and stereomorphological analysis was carried out with the help of microphotos of serial semi-thin histological sections of the pancreas of the examined people. Stereomorphological analysis was carried out by the method of multilayer plastic reconstruction. It was found that the pancreas of a newborn baby is a definitive functional organ that differs morphologically from that of an adult in some features, namely, in the relative predominance of a volume of interstitial space in the pancreas of a newborn human. Within the individual glandular lobule, the interstitial space is a complexly branched labyrinth consisting of interconnected interacinal gaps of different shapes and widths. The widest and most hydrated of them (nodal interstitial “compartments”), which are considered as extravascular channels, are located around the intra-lobular and general lobular ducts and conduct the fluid to the appropriate groups of secretory cells.

pancreas, lobe, interstitial space, end sections, excretory ducts

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«Bulletin of problems biology and medicine» Issue 4 Part 3 (141), 2017 year, 314-318 pages, index UDK 616.37:611.74(-053)

10.29254/2077–4214–2017–4–3–141–314-318