AESTHETIC DERMATOLOGY, AS AN AREA FOR THE USE OF RESISTANT AND PERMANENT IMPLANTS. PATHOMORPHOLOGICAL ESTIMATION OF EFFICIENCY

Turkevych M., Turkevych A.

MORPHOLOGY

Scentific article

Aim: determine effectiveness of collagenogenesis as a result of setting of resorbing and permanent implants on the basis of study pathomorphological changes in the skin. Object and methods: the studies were performed on 30 mature white male rats of the “Vistar” line weighing 100-130 g. Experimental animals were divided into 2 groups depending on the type of implanted threads. The rats of all groups (14, 30 and 90 days) were divided into 3 subgroups each of them consisting from 10 individuals. For all 10 rats of each subgroup, the same type of suture material was implanted. The following Aptos threads were used during the experiment: Excellence Visage (EV) and Aptos Spring (AS). Results. During study of morphological changes in the perimplant zone, it was found that in all groups of experimental rats, on different chronological stages the collagen with different biodegradation time and in different quantities is formed. Dependence between type of implantation thread (structure) and stimulation of collagenogenesis has been established. Conclusions 1. While studying morphological changes in the perimplant zone, it was found that in all groups of experimental rats, collagen with different term of biodegradation and in different quantities on various chronological stages is formed. 2. It was established that collagenogenesis is stimulated unevenly, depending on the type of implantation thread (chemical composition and structure). 3. On the 90th day of the experiment, the resorbing thread did not completely degrade, which does not contradict the information provided by the manufacturer about the period of disintegration (365 days), and the expediency of using these cosmetic threads in aesthetic dermatology for the purpose of prolonged lifting skin correction. 4. The specificity of the structure of implant threads, namely the form of a spring (AS), as a provocative factor for long-term alteration, causes long-term inflammatory response in tissues (90th day of the experiment).

collagen, collagenogenesis, permanent implants, resorbing implants

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«Bulletin of problems biology and medicine» Issue 4 Part 3 (141), 2017 year, 319-323 pages, index UDK 616.5:111.852]:616-089.843-091

10.29254/2077–4214–2017–4–3–141–319-323