MORPHOLOGICAL AND TOPOGRAPHIC PECULARITIES OF THE UTERUS OF FEMALE WHITE RAT

Mota O. M., Podoliuk M. W., Rosenkow S. O., Mariiko I. M.

MORPHOLOGY

Scentific article

Taking into consideration the incessant growth of pathology of organs of female reproductive system and congenital abnormalities, the comparison of morphological pecularities of human genitals and female rats is quite necessary. According to data of literature abnormalities of the Mueller ducts occur in 4,3-6,7% of women. In the structure of these abnormalities bicornuate uterus plays an important role. It is known that the patients with bicornuate uterus have much bigger chances of miscarriages and precocious delivery (36 and 23% accordingly). This given abnormality may be a reason of other problems such as dysmenorrhoea, amenorrhoea, abdominal pain and recurrent pain. The uterus of white rat in its norm belongs to bicornuate and a question about possibility of using it as a model of appropriate defect in a human being with next development of new methods of treatment and successful pregnancy management and delivery in women with given abnormality is actual enough. Macroanatomy and syntopia of the uterus of eight female white rats weighing 200-230 gr aged 4,5-5 months have been studied. The uterus of female white rat consists of two spurs, which are connected, forming common cervix of the uterus that is located in the pelvic cavity and spurs rise to abdominal cavity and their tops together with ovaries and twisted uterine tubes are adjacent to the lower poles of the kidneys. The average weight of the uterus is 0,88 gr and it is 0,38% from general weight of rat; on average, the weight of the uterus of a woman who has not given birth is 50 gr which is 0,083% of body weight. Asymmetry of uterine spurs is observed: the right spur is on average 2 sm longer than the left one, howewer, external diameter of the left spur exceeds on average 1 mm the same size of the right one. The length of cervix is 1,1 sm, and external diameter – 5 mm. There are two slit-like cavities in the cervix each of them are connected to the lumen of one of the spurs. Hence, morphologically the uterus of female rat has considerable similarity to such abnormality as bicornuate uterus in human. There are certain devergences: the spurs of the uterus of a rat have considerable length and go beyond the pelvic cavity.

uterus, female rat, morphology, syntopy

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«Bulletin of problems biology and medicine» Issue 2 Part 2 (165), 2022 year, 98-101 pages, index UDK 611.441:599.23]-019

10.29254/2077-4214-2022-2-2-165-98-101