Fedotova O. L.


About the author:

Fedotova O. L.



Type of article:

Scentific article


The purpose of the study was to study the dynamics of the peculiarities of the representatives of the microbiota of the oral mucosal membrane during orthopedic rehabilitation of patients with removable structures with a obturating part with two-layer bases. To achieve this goal, bacteriological examination of oral cavity mucosa was performed for 25 patients with partial adenia of the upper jaw and defect of hard palate and alveolar process. The results of the conducted studies indicate significant shifts in the qualitative and quantitative composition of microbiocenosis in the oral cavity in patients with partial adenia of the upper jaw and a defect of hard palate and alveolar process due to representatives of moraksel, enterobacteria (representatives of the genera Klebsiella and E. coli). Comparison of the frequency of extraction and the density of microbial colonization showed the persistence in the given biotope of representatives of 13 genera of bacteria and yeast-like fungi of the genus Candida in averages from lg (2,5 ± 0,19) to lg (5,4 ± 0,17) NCU/g. For patients who have been made a two-layered basis based on carboxymethylcellulose and polyvinialacetate in the period of adaptation to a removable prosthesis, it was characteristic that the detection of 5 component associations at 30 days was reduced by 2 times (χ2 = 5,991; ν = 2; p <0,05). The frequency of removal and density of microbial colonization of the experimental group did not differ statistically.Among patients in the control group, the microbial colonization density increased for Enterococcus spp, for Klebsiella spp and for Candida spp. Yeast-like fungi. A significant decrease in the microbial density of the resident microflora was 1.4 times for Neisseria spp, 1.6 times for Lactobacillus spp (p <0,05). The revealed microbiological features in adentiy patients dictate the need to include a scheme for correction of microbiocenosis in the oral cavity of patients with partial adenia of the upper jaw and defect of hard palate and alveolar process of the agents having a directed anti-inflammatory action and providing recovery and storage of the normal biocenosis of said biotope.


microecology, two-layer basis, removable prosthesis, obturating part, mucous membrane of oral cavity


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Publication of the article:

«Bulletin of problems biology and medicine» Issue 1 Part 1 (148), 2019 year, 356-361 pages, index UDK 616.314-089.23-77-078:57.083.1