SKIN MICROBIOCENOSIS IN PATIENTS WITH PYODERMA
About the author:
Andrashko Yu. V., Alarqan Mohammad Ahmad
Heading:
CLINICAL AND EXPERIMENTAL MEDICINE
Type of article:
Scentific article
Annotation:
Pyoderma means any skin disease that is pyogenic. Pyoderma is primary or secondary and superficial or deep. Primary pyoderma, includes superficial bacterial infections such as Impetigo, ecthyma, folliculitis, furuncle, carbuncle, abscess, etc. Secondary pyoderma is primarily caused by conditions that involve bacterial infections below the epidermal layer of skin. Some conditions that contribute to the secondary pyodermas are ectoparasite infestations, fungal infections, atopic or contact type allergic responses, a weakened immune system as a result of poor nutrition or prolonged steroid use, cancer, or endocrine diseases like diabetes, hypothyroidism. Pyodermas are quite common worldwide and constitute a major portion of the cases in Dermatology clinics (about 30-40%). Many cases these days do not respond to the antibiotics that were previously very effective in such cases. Considering these aspects, the present study was an attempt to investigate of skin microbiocenosis features in patients with pyoderma. Object and methods. 103 patients (65 males and 38 females) who attended to Zakarpattia Regional Dermatology Clinic were screened for pyogenic skin infections of both primary and secondary types. Sterile swabs were used to aseptically collect exudate or pus from the lesions. Care was taken that these samples were collected before the start of antibiotic therapy. The swabs were transported immediately to the microbiology laboratory for culture and sensitivity examination. Statistic processing of data was performed using a software package Microsoft XP «Excel» and standard version of «Statistica for Windows 12.0» (StatSoft, Tulsa, OK, USA). Statistically significant was p-value of p<0.05. Results. Among all observed patients in 14 persons we detected of impetigo, in 15 cases – furunculosis; in 36 cases – chronic superficial and in 38 cases – chronic deep pyoderma. S. aureus, Str. pyogenes, S. epidermidis, S. saprophyticus, E. coli were isolated from all observed patients. In rare cases we detected of Micrococcus, Bacillus, Sarcina, Acinеtobacter etc. In patients with acute pyoderma, regardless of the depth of the pathological process, there were a biinfection of lesions with obligatory presence in the microbial associations of S. aureus with the incidence of participation in them of «other microorganisms» (Micrococcus, Bacillus, Sarcina, Acinetobacter) and the emergence of E. coli. Chronic pyodermas, both superficial and deep, are characterized by more branching of microbial compositions and the growth of the specific gravity of E. coli and other microorganisms. In addition, the pustular skin diseases, regardless of the clinical course, is characterized by excessive growth of S. aureus, Str. pyogenes, S. epidermidis, S. saprophyticus, E. coli and «other microorganisms». Conclusion. The microbiota of skin in patients with pyoderma is difference. This aspect caused of individual management of pyoderma.
Tags:
pyoderma, diagnosis, skin microorganisms.
Bibliography:
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Publication of the article:
«Bulletin of problems biology and medicine» Issue 1 Part 2 (149), 2019 year, 105-108 pages, index UDK 616.5-002.33+616.5-078