DYSFUNCTION OF THE SALIVARY GLANDS – ACTUAL MEDICAL AND SOCIAL PROBLEM

Yeroshenko G. A., Shevchenko K. V., Kramarenko D. R., Vilkhova O. V., Yachmin A. I.

LITERATURE REVIEWS

Scentific article

The salivary glands, the secret of which is saliva, is endowed with four main functions: synthetic, endocrine, filtration and barrier (participation in the formation of local immunity). The importance of the full functioning of the salivary glands is associated with the activity of various organs and systems of the body, since the salivary glands, possessing various functions, have the ability to peculiar reactions to various external influences and intraorganic disorders. The decrease of functional activity of the salivary glands can have serious negative consequences, which lead to deterioration of the cleansing of the organs of the oral cavity, as a consequence, to the violation of hygiene, there is a decrease in the resistance of the enamel, decreases local immunity, there is a negative effect on homeostasis in the oral cavity. The hypofunction of the salivary glands is observed in endocrine diseases, iron deficiency anemia and hypovitaminosis A. The decrease of the function of the salivary glands of the organic genesis is observed with lesions of the inflammatory and noninflammatory nature: sialadenitis, sialozoadenitis, neoplasms of the salivary glands, wounds of the salivary glands and their ducts, which is confirmed by exudative changes in peripartal interstitium and intercellular connective tissue, formation of leukocyte periductal infiltrates with the involvement of polymorphonuclear leucocytes, circulatory disorders accompanied by disruption of connective tissue with the development of mucoid swelling, changes in the structural components of the parenchyma of submandibular gland – vacuolization of cytoplasm glfnduocytes of the tnd-pieces and changes in their tinctorial properties desquamation of the ductal epithelia, condensation of chromatin in epithelial cells, impaired of the secret formation and secretion in cells of the granular ducts, increase in the average of the lumens’ diameter and a decrease in the height of the epitheliocyte in the endpieces and intercalated ducts, by decreasing the mean values of the outer diameters of the intercalated, straited and granular ducts. The great influence on the work and violation of the functioning of the salivary glands has the state of parts of the hemomycocirculatory bed. Thus, the salivary glands, performing a number of important physiological processes, play a significant role in maintaining the homeostasis of the oral cavity, and the normal work of the salivary glands is a prerequisite not only for the implementation of almost all processes that occur in the oral cavity, but also in the body as a whole.

dysfunction, salivary glands, saliva, xerostomia, diasise.

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«Bulletin of problems biology and medicine» Issue 2 Part 1 (150), 2019 year, 22-26 pages, index UDK 616.316-084

10.29254/2077-4214-2019-2-1-150-22-26