SOCIO-DEMOGRAPHIC CHARACTERISTICS OF PATIENTS WITH COGNITIVE IMPAIRMENT IN DEPRESSIVE DISORDERS

Yaroslavtsev S. O.

CLINICAL AND EXPERIMENTAL MEDICINE

Scentific article

362 patients with cognitive impairment in depressive disorders were examined: 123 patients with recurrent depressive disorder (RDD), 141 patients with bipolar affective disorder (BAD) and 98 people with prolonged depressive reaction (PDR). Socio-demographic characteristics included distribution by age, sex, level of education, marital status, characteristics and sphere of professional activity and place of residence. Socio-demographic indicators of patients with cognitive impairment in depressive disorders were determined. It was found that among the examined persons prevalence of females (51,96 %), only in the group of patients with BAD there were more men (53,90 %). Persons aged 30-44 years prevailed (38,12 %). There were more young people (18-29 years) among patients with PDR (21,43 %) and BAD (31.21 %), and middle-aged people (45-59 years) and the elderly (60-65 years) were more among patients with RDD (37,40 % and 17,07 %). The level of education in patients with cognitive impairment in depressive disorders was dominated by persons with secondary specialized (33,25 %) and graduated education (33,26 %). The majority of patients were city residents (66,46 %), married (34,91 %), among patients with PDR there were more single people (41,84 %), among patients with RDD and BAD were more divorced persons (21,95 % and 26,95 %, respectively). In terms of employment, patients with cognitive impairments in depressive disorders were characterized by a predominance of working people (48,63 %), who were mainly engaged in mental work (61,22 %); 29,58 % of patients were unemployed, 21,77 % patients were retired. The number of persons with physical nature of work was higher among patients with PDR (54,72 %) than with RDD and BAD (36,21 % and 25,40 %, respectively), among whom patients with mental nature of work prevailed (63,79 % and 74,60 %, respectively) and there were more pensioners (27,64 % and 23,40 %, respectively). Hereditary burden of the main disease with somatic pathology was found in 90 patients with depressive disorders (24,86 %), the presence of alcohol dependence in relatives was found in 71 patients with depressive disorders (19,61 %) and the presence of depressive disorders in relatives was found in 64 patients with depressive disorders (17,68 %). At the same time, hereditary burden of depressive disorders distinguished patients with RDD and BAD from patients with PDR (21,95 %, p = 0.009 and 19,15 %, p = 0.024, respectively), among whom there were more patients with hereditary burden in the form of personality anomalies in relatives (8,13 %, p = 0.012 and 9,93 %, p = 0.026, respectively). Thus, certain socio-demographic characteristics of patients with cognitive impairment in depressive disorders should be taken into account in the differential diagnosis of these disorders.

patients with cognitive impairment, depressive disorders, socio-demographic characteristics, recurrent depressive disorder, bipolar depressive disorder, prolonged depressive reaction.

1. Krasnov VN. Rasstroystva affektivnogo spektra. Prakticheskaya meditsina: 2011. 432 s. [in Russiаn].
2. Shmunk YeV. Faktory, okazyvayushchiye vliyaniye na kliniku i techeniye depressivnykh rasstroystv. Sotsial’naya i klinicheskaya psikhiatriya. 2009;19(2):87-92. [in Russiаn].
3. Wittchen HU, Jacobi F, Rehm J. The size and burden of mental disorders and other disorders of the brain in Europe 2010. Eur Neuropsychopharmacol. 2011 Sep;21(9):655-79. DOI: 10.1016/j.euroneuro.2011.07.018
4. Corruble E, Belaidi C, Goodwin GM. Agomelatine versus escitalopram in major depressive disorders: a randomized double-blind, long term study focusing on sleep satisfaction and emotional blunting. J European Psychiatry. 2011;26(1); Abstracts of 19th European Congress of Psychiatry (March 12-15, 2011, Vienna, Austria). Part 2. p. 24.
5. Maruta NA, Fedchenko VYu. Clinical-Psychopathological and Pathopsychological Prognostic Factors of Recurrent Depressive Disorders Course. Psikhiatriya, psikhoterapiya i klinicheskaya psikhologiya. 2019;1:120-34.
6. Silverstein B, Edwards T, Gamma A. The role played by depression associated with somatic symptomatology in accounting for the gender difference in the prevalence of depression. Soc Psychiatry Psychiatr Epidemiol. 2013 Feb;48(2):257-63. Available from: https://doi. org/10.1007/s00127-012-0540-7
7. Maruta NA, Yur’yeva LN. Depressiya i trevoga v praktike vracha somaticheskogo profilya. Zdorov’ya Ukraí̈ni. 2010;2(13):54-5. [in Russiаn].
8. Blanco C, Vesga-Lopez O, Stewart J. Epidemiology of major depression with atypical features: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). J Clin Psychiatry. 2012 Feb;73(2):224-32. DOI: 10.4088/JCP.10m06227
9. Tyuvina NA, Voronina YeO, Balabanova VV, Tyul’pin YuG. Klinicheskiye osobennosti depressii u zhenshchin v sravnenii s muzhchinami. Nevrologiya, neyropsikhiatriya, psikhosomatika. 2018;10(3):48-53. [in Russiаn].
10. Yanushko MG, Shamanina MV, Ivanov MV. Pokazateli kognitivnogo funktsionirovaniya u patsiyentov s rekurrentnym depressivnym rasstroystvom. Sotsial’naya i klinicheskaya psikhiatriya. 2017;27(3):26-31. [in Russiаn].
11. Ferrari AJ, Charlson FJ, Norman RE, Patten SB, Freedman G, Murray C, et al. Burden of depressive disorders by country, sex, age, and year: findings from the global burden of disease study 2010. PLoS Med. 2013 Nov;10:e1001547. Available from: https://doi.org/10.1371/ journal.pmed.1001547
12. Maruta NA. Diagnostika i terapiya unipolyarnykh depressiy v sovremennykh usloviyakh: mify i real’nost. Nezavisimyy psikhiatricheskiy zhurnal. 2012;IV:8-15. [in Russiаn].
13. Hasselbalch BJ, Knorr U, Kessing LV. Cognitive impairment in the remitted state of unipolar depressive disorder: a systematic review. J. Affect. Disord. 2011;134:20-31.
14. Polishchuk YuI, Kalinichenko TP, Letnikova ZV. Rasstroystva depressivnogo spektra u potrebiteley uslug tsentrov sotsial’nogo obsluzhivaniya (sravnitel’no-vozrastnoy aspekt). Rossiyskiy psikhiatricheskiy zhurnal. 2017;4:41-6. [in Russiаn].

«Bulletin of problems biology and medicine» Issue 3 (157), 2020 year, 165-169 pages, index UDK 616.8-008.64:616.89-008.46:159.943:314.04-052

10.29254/2077-4214-2020-3-157-165-169