ВЛИЯНИЕ АНТИОКСИДАНТОВ НА ФРАГМЕНТАЦИЮ ДНК СПЕРМАТОЗОИДОВ

Украинская С. И., Литвиненко А. П., Калейникова О. Н.

ОБЗОРЫ ЛИТЕРАТУРЫ

Научная статья.

Индекс фрагментации ДНК является важным маркером мужского бесплодия и может в значительной степени снижать эффективность мер, принимаемых в рамках вспомогательных репродуктивных технологий. Целью работы был поиск и анализ данных литературы о влиянии антиоксидантов на фрагментацию ДНК сперматозоидов. Показано влияние оксидативного стресса, активных форм кислорода и антиоксидантов на данный показатель и общую активность сперматозоидов. В настоящее время роль антиоксидантной терапии в лечении мужского бесплодия требует дальнейшего исследования как in vivо, так и in vitro.

индекс фрагментаций ДНК сперматозоидов, активная форма кислорода, оксидативный стресс.

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«Вестник проблем биологии и медицины» Выпуск 1 (155), 2020 год, 58-61 страницы, код УДК 616.699-07:577.2.088.7

10.29254/2077-4214-2020-1-155-58-61