EFFECT OF SODIUM GLUTAMATE ON THE RESPIRATORY SYSTEM IN RATS

Yeroshenko G. A., Donets I. M., Shevchenko K. V., Grigorenko A. S., Kinash O. V., Lisachenko O. D.

LITERATURE REVIEWS

Scentific article

The paper analyzes the data of literature sources on the effect of monosodium glutamate on the respiratory system, their structural features and reactions. The use of food additives is highly controversial, both in the scientific community and in the public, mainly due to the lack of thorough research on their effects on the human body. Studies have not provided a definitive answer to the varying degrees of human susceptibility to the effects of dietary supplements, and data on their combined effects are lacking. Of particular concern to domestic and foreign scientists is the fact of widespread use of food additives in food. The most important hygienic feature of the production of specialized products for baby and dietary nutrition, the researchers insist, is the restriction of the use of food additives and the categorical ban on the use of synthetic impurities. In the 1980s, scientists actively analyzed the effects of monosodium glutamate on the airways in patients with chronic stable asthma. The researchers concluded that further clinical and epidemiological studies were needed. A critical analysis of the existing literature shows that many of the negative health effects of monosodium glutamate are uninformative because they are based on an overdose that does not meet the standards normally consumed in food. Thus, it was found that the use of monosodium glutamate leads to microcirculation disorders in the lungs and congestion in the venous segment. During research, inflammation is observed, in addition to the processes of decomposition, which are characterized by the breakdown of carbohydrates, fats, proteins, depolymerization of protein-polysaccharide complexes and the appearance of underoxidized metabolic products, and the synthesis processes begin to intensify. In this process, fibroblasts, connective tissue cells of the lungs, which have high synthesis activity, and histiocytes, which play a protective role, become important.

respiratory system, lungs, structure, food additives, sodium glutamate, rats.

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«Bulletin of problems biology and medicine» Issue 3 (161), 2021 year, 31-34 pages, index UDK 613.295(604.4:663.051):616.2-092.9

10.29254/2077-4214-2021-3-161-31-34