THE MAIN CARDIOVASCULAR RISK-FACTORS IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION WITH ST ELEVATION

Vakaliuk I. P., Iyad Ali Ibrahim Alghzawi

CLINICAL AND EXPERIMENTAL MEDICINE

Scentific article

The 2016 Heart Disease and Stroke Statistics update of the American Heart Association has recently reported that 15.5 million persons 20 and more years of age in the USA have CHD, whilst the reported prevalence increases with age for both women and men and it has been estimated that approximately every 42 seconds, an American will suffer for an myocardial infarction (MI). There are modified and unmodified cardiovascular risk-factors. Among them the main burden on prognosis has arterial hypertension, diabetes, smoking and dyslipidemia. The purpose of study was evaluation of main cardiovascular risk-factors prevalence in patients with acute myocardial infarction with ST elevation (STEMI). Object and methods: 100 patients both males and females hospitalized with STEMI were observed. The general clinical tests and lipidogramma were performed. Analyses were performed with “Statistica” system software, version 12.0. The study was performed in accordance with the Helsinki Declaration and Good Clinical Practice Guideline. Results: there are 64 males and 36 females among observed patients with STEMI. The average age was (65.85±11.64) years. Due the age aspect males were younger for 10 years then females. Arterial hypertension was verified in 82% cases without any gender differences in its prevalence. The average data of blood pressure at admission were: (130.61±2.22) mm Hg for systolic blood pressure and (80.32±1.25) mm Hg – for diastolic blood pressure. Uncontrolled hypertension was observed in 26 cases. Diabetes mellitus 2 type was detected in 16 patients with STEMI. The frequency of its identification in females was insignificant higher than in males: 25%, versus 10,9% (χ2 =3,39; p=0,066). All patients with diabetes 2 type comorbidity suffered from arterial hypertension. Active smokers at admission were 32 patients (all were males). The main sings of dyslipidemia were hypercholesterolemia and high levels of LDL-C in plasma. Thus, the average total cholesterol level was (5.35±0.16) mmol/l; LDL cholesterol – (3.81±0.15) mmol/l; triglycerides – (1.50±0.09) mmol/l and HDL cholesterol – (2.52±0.31) mmol/l. No significant gender difference in plasma lipids concentrations was verified. Conclusion. The main prevalence cardiovascular risk-factors among patients with STEMI are arterial hypertension and dyslipidemia (high plasma levels of total cholesterol and low density lipoproteins cholesterol). It’s an additional burden for clinical course of myocardial infarction.

STEMI, arterial hypertension, risk factors, dyslipidemia

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«Bulletin of problems biology and medicine» Issue 2 Part 2 (151), 2019 year, 91-93 pages, index UDK 616.127-005.8+ 616.12-071.6

10.29254/2077-4214-2019-2-2-151-91-93