Savchenko A. A., Vikhtyuk T. I., Kobza I. I.

CHANGES IN BLOOD CIRCULATION AND DAMAGE TO THE MAIN VESSELS OF THE NECK WITH THE DEVELOPMENT OF THE CAROTID BODY TUMOR


About the author:

Savchenko A. A., Vikhtyuk T. I., Kobza I. I.

Heading:

CLINICAL AND EXPERIMENTAL MEDICINE

Type of article:

Scentific article

Annotation:

Abstract. Objective. To improve the results of surgical treatment of patients with carotide body tumor through the study of the features of lesions of the major vessels of the neck. Materials and methods The analysis of the clinical symptoms of 72 patients who were hospitalized in the department of vascular surgery Lviv regional hospital for the period 1997 to 2017 in this group of patients in the 42 case diagnosed the carotid body tumor (study group) and 30 cases of tumors other oncogenesis in section of carotid arteries (control group). The calculation of statistical indicators performed using Excel 2010 with the definition of reliability of the results based on Fisher test. Results and discussion. Based on the data of ultrasound examination, computer tomography and the results of surgical intervention in patients with carotid body tumors, we observed thrombosis of jugular vein – 4.76% (p=0.1931), invasion in the vascular wall – 21.43% (p=0, 5344), the deviation of the internal carotid artery is 30.95% (p=0.0173, OR 6.86, 95%, 1.3-30.4), compression – 90.48% (p=0,0552). At the same time, the degree of stenosis of carotid arteries did not exceed 60%. In patients of the control group thrombosis of jugular vein was found in 13.33%, invasion in the wall of carotid arteries in 23.33%, deviation of the internal carotid artery in 10.0%, compression with the development of stenosis in 73.33%. Statistical analysis between groups showed a significant difference, that for carotid body tumor typical is compression on the vascular wall with the development of deviation of the internal carotid artery. The results of the study show that in case of carotide body tumor in one third of cases there is a deviation of the internal carotid artery. Therefore, in such patients, surgical interventions require the technique of correction of residual deformations of the internal carotid artery, which causes the resection and redistribution of the common carotid artery

Tags:

carotid body tumor, internal carotid artery, neck arteria and vein, surgical treatment.

Bibliography:

  1. Karatas E, Sirikci A, Baglam T. Synchronous bilateral carotid body tumor and vagal paraganglioma: a case report and review of literature. Auris Nasus Larynx. 2008;35(1):175.
  2. Naughton J, Morley E, Chan D, Fong Y, Bosanquet D, Lewis M. Carotid body tumours. Br J Hosp Med. 2011;72(10):559-64.
  3. Boscarino G, Parente E, Minelli F, Ferrante A, Snider F. An evaluation on management of carotid body tumour (CBT). A twelve years experience. Giornale di Chirurgia. 2014;35(1-2):47-51.
  4. Gad A, Sayed A. Carotid body tumors: a review of 25 years experience in diagnosis and management of 56 tumors. Ann Vasc Dis. 2015;7(3):292-9.
  5. Li-Shan L, Chang-Wei L, Heng G, Yue-Hong Z, Xing-Ming C, Yong-Jun L. Efficacy of surgical therapy for carotid body tumors. Chin Med Sci. J. 2011;26(4):241-5.
  6. Naik SM, Shenoy A, Nanjundappa M, Halkud R, Chavan P, Sidappa K, et al. Paragangliomas of the carotid body: current management protocols and review of literature. Indian J Surg Oncol. 2013;4:305-12.
  7. Sajid MS, Hamilton G, Baker DM. A multicenter review of carotid body tumour management. Europ J Vasc.Endovasc Surg. 2007;34:127- 31.
  8. Nader M. Albsoul carotid body paraganglioma management and outcome. Europ J Scien Res. 2009;37:567-74.
  9. Tonn J-C, Westphal M, James TR. Onkology of CNS Tumors. London: Springer Heidelberg Dordrecht. 2010;2:299-307.
  10. Harrison LB, Sessions RB, Waun KH. Head and Neck Cancer: a multidisciplinary approach. Philadelphia: Lippincott Williams and Wilkins; Wolters Kluwer. 2009;3:655-80.
  11. Shah HM, Gemmete JJ, Chaudhary N, Pandey AS, Ansari SA. Preliminary experience with the percutaneous embolization of paragangliomas at the carotid bifurcation using only ethylene vinyl alcohol copolymer (EVOH). Onyx J Neurointerv Surg. 2012;4:125-9
  12. San Norberto EM, Taylor JH, Carrera S, Vaquero C. Intraoperative embolization with poloxamer 407 during surgical resection of a carotid body tumor. J Vasc Surg. 2012;56:1782-5
  13. Sen I, Stephen E, Malepathi K, Agarwal S, Shyamkumar NK, Mammen S. Neurological complications in carotid body tumors: A 6-year single-center experience. J Vasc Surg. 2013; 57(2): 64–8.
  14. Soh AW, Kek PC. Dopamine-secreting carotid body paragangliomas-biochemical control with radiotherapy. Intern. Med. 2012; 51: 613- 8.

Publication of the article:

«Bulletin of problems biology and medicine» Issue 4 (162), 2021 year, 172-176 pages, index UDK 616.13:616.471-006.6-089

DOI: