INFLUENCE OF ANEMIA ON THE SERIOUSNESS OF CHD

Khaniukov O. O., Zaiats I. O., Pesotskaia L. A., Derkach A. K., Bashta I. G.

CLINICAL AND EXPERIMENTAL MEDICINE

Scentific article

Ischemic heart disease is the most common cause of morbidity and mortality among all cardiovascular diseases worldwide, while atrial fibrillation (AF) is the most common cardiac arrhythmia. AF is a well-known factor in the unfavorable short-term and long-term prognosis in patients with acute myocardial infarction (AMI) and is associated with an increase in overall mortality. Analysis of the literature has shown that the presence of anemia, including mild to moderate severity increases short-term and long-term outcomes in patients with acute myocardial infarction (AMI). Against the background of anemia, the risk of death increases in both systolic and diastolic heart failure, reduced tolerance to exercise, quality of life and worsens the prognosis in patients. Iron deficiency anemia and iron deficiency without anemia contribute to the progression of heart failure and are a predictor of unfavorable prognosis. The aim of our study was to assess the duration of hospitalization and the severity of the clinical picture in patients with mild to moderate anemia. According to the results of the study, patients with coronary heart disease in combination with anemia were significantly more likely (p<0.05) to complain of general fatigue, shortness of breath, edema, dizziness than patients without anemia. Anemia significantly affected the duration of hospitalizations – 13.2±0.7 bed days in the main group against 10.3±0.2 bed-days – in the control group (p<0.001), which is more often associated with the progression of CHF and greater decrease in exercise tolerance in patients with concomitant anemia than without it (100% in the main group and 88.2% in the control group). Patients with anemia had a higher degree of heart failure and were more likely to be prescribed diuretics than patients without anemia. Patients with anemia were more likely to be hospitalized for AMI than patients without anemia. There was also a greater decrease in exercise tolerance in patients with concomitant anemia than without it. Prospects for further research are a more detailed analysis of the clinical course, parameters of laboratory, instrumental research methods in patients with coronary heart disease and coronary heart disease and anemia, taking into account the commitment of patients to treatment.

coronary heart disease, anemia, comorbid conditions, complications, severity

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«Bulletin of problems biology and medicine» Issue 4 (162), 2021 year, 199-203 pages, index UDK 616.12-005.4:616.155.194]-06-036-07

10.29254/2077-4214-2021-4-162-199-203