PROPHYLAXIS OF DEVELOPMENT OF VENOUS TROMBOEMBOLISM FOR PATIENTS FROM CORONAVIRUS BY ILLNESS

Nekhanevych O. B., Gashinova K. Y., Tuituinnik M. A., Manin M. V., Korota Y. V

CLINICAL AND EXPERIMENTAL MEDICINE

Scentific article

Abstract. The problem of prevention of thromboembolic complications is one of the key problems for the health care system, which is extremely relevant in connection with the rapid spread of COVID-19, because today venous thromboembolism is recognized as one of the most serious complications in patients with COVID-19 in the intensive care unit is from 25 to 69%. Studies have shown that SARS-CoV-2 causes disorders of the blood coagulation system, which is the cause of venous thromboembolism. The solution to this problem is to establish criteria for assessing the risk of thromboembolic complications, as well as the development and implementation of prevention methods. Therefore, the development of differentiated methods of therapeutic exercises for the prevention of thromboembolic complications in patients with coronavirus disease is extremely relevant. The aim of the study. Improving the effectiveness of measures to prevent the development of venous thromboembolism in coronavirus disease by developing and substantiating methods for assessing the risk of thromboembolic complications and differentiated methods of therapeutic exercises for the prevention of thromboembolic complications. Object and methods of research. The observation included inpatients (with a confirmed diagnosis of COVID-19 by polymerase chain reaction) of the therapeutic department and the department of occupational pathology of the City Clinical Hospital № 4 “Dnipropetrovsk City Council” aged 39 to 81 years (mean age was 60.5±2.3 years), in the amount of 20 people. Among those surveyed were 15 women (75%) and 5 men (15%). Methods. The level of physical development was investigated using the method of anthropometry, the level of blood saturation was determined by pulse oximetry, body temperature – thermometry with a mercury thermometer in the groin area, heart rate was measured using the method of pulsometry (artery measurement was used). All indicators were studied according to standard methods. The study diagnosed the psychological state of patients, as well as the physical health of patients, in order to determine the general condition of patients. In the course of the work, the medical histories of these patients were developed to identify risk factors for venous thromboembolism and to analyze the probability of developing venous thromboembolism in the studied patients using the developed method of risk assessment of thromboembolic complications. As a result, it was determined that 5% of patients have a low level of complications, 5% – moderate, 35% – high, and 55% – very high. Regarding the frequency of manifestation of certain factors, acute infection (pneumonia) was detected in 100% of inpatients, age over 41 years – in 95%, immobilization (presumed need of bed rest (with the ability to use the bathroom/toilet) due to reduced motor activity of the patient more than 3 days) – in 70%, and obesity – in 45% of patients. Based on the processed information on the symptoms of coronavirus disease, general well-being and opportunities for physical activity in different courses of the disease, as well as data obtained during the study was created and substantiated differentiated (for different forms of coronavirus disease developed different methods, respectively) prevention of thromboembolic complications in coronary heart disease. Conclusions. A method for assessing the risk of thromboembolic complications in patients with coronavirus disease was developed and implemented, on the basis of which a study of patients was conducted to assess the likelihood of venous thromboembolism. A differentiated method of therapeutic exercises for the prevention of thromboembolic complications in patients with coronavirus disease has been developed, which provides an opportunity to prevent the development of venous thromboembolism in patients at risk.

prevention, thromboembolic complications, coronavirus disease, therapeutic exercises.

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«Bulletin of problems biology and medicine» Issue 1 (159), 2021 year, 93-97 pages, index UDK 616.24-002:616.98:578.834]-036.82:615.825

10.29254/2077-4214-2021-1-159-93-97