Aliyev M. Kh., Museibov E. A.


About the author:

Aliyev M. Kh., Museibov E. A.



Type of article:

Scentific article


The question of studying the characteristics of sensitivity / resistance of bacteria isolated from patients with urolithiasis in order to develop optimal therapy and correct complications in patients with a urological profile is relevant. Purpose of the study. Study of the etiological structure and level of antibiotic resistance of pathogens of infectious and inflammatory complications of infections in patients with a urological profile. Methods. The case histories of 345 patients who were treated in the urology department with a diagnosis of urolithiasis, male and female over the age of 18, were studied. The material for bacteriological studies was urine. Results. When analyzing age indicators, it was found that adults over the age of 31-40 years are more likely to be at risk of developing the studied infections. Infectious and inflammatory complications were presented: acute pyelonephritis, acute cystitis. The spectrum of pathogens of infectious and inflammatory complications of the urinary tract in patients after long-distance lithotripsy is mainly represented by gram-negative flora: E. coli, Ps. aeruginosa, Proteus spp. Staphylococcus sapr prevailed among representatives of gram-positive pathogens. The most effective drugs against Ps strains. Aeruginosa proved to be polymyxin, cephalexin. Almost all Klebsiella strains showed high sensitivity to cephalotin and cephalexin. Microorganisms of the genus Proteus showed high sensitivity to gentamicin and cephalexin. Сonclusion. It is advisable to use the data when choosing the starting empirical antibiotic therapy in the development of the leading complications of distant lithotripsy.


lithotripsy, urinary tract infections, pathogens, antibiotic resistance.


  1. Bonkat G, Pickard R, Bartoletti R, Guidelines Associates: A. Pilatz, B. Pradere, R. Veeratterapillay. EAU Guidelines on Urological Infections. Edition presented at the EAU Annual Congress Copenhagen 2018. ISBN 2018.
  2.  Khalid A. Al-Rubeaan, Osama MoharramDekra, Al-NaqebAsim Hassan M, Rafiullah RM. Prevalence of urinary tract infection and risk factors among Saudi patients with diabetes. World J Urol. 2013;31:573-8.
  3. Bader MS, Hawboldt J, Brooks A. Management of complicated urinary tract infections in the era of antimicrobial resistance. Postgrad Med. 2010;122(6):7-15.
  4. Kahlmeter G, ECO.SENS. An international survey on the antimicrobial susceptibility of pathogens from uncomplicated urinary tract infections: the ECO.SENS Project. J Antimicrob Chemother. 2003;51:69-76.
  5. Schito GC, Naber KG, Botto H, Palou J, Mazzei T, Gualco L, et al. The ARESC study: an international survey on the antimicrobial resistance of pathogens involved in uncomplicated urinary tract infections. Int J Antimicrob Agents. 2009;34(5):407-13.
  6.  Stone L. Which antibiotics for UTI? Nat Rev Urol. 2018;15(7):396.
  7. Gupta K, Hooton TM, Naber KG. Infectious Diseases Society of America; European Society for Microbiology and Infectious Diseases. International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the infectious diseases society of America and the European society for microbiology and infectious diseases. Clin Infect Dis. 2011;52(5):e103-e20.
  8.  Matuschek E, Brown DF, Kahlmeter G. Development of the EUCAST disk diffusion antimicrobial susceptibility testing method and its implementation in routine microbiology laboratories. Clin Microbiol and Infect. 2014;20(4):255-66.

Publication of the article:

«Bulletin of problems biology and medicine» Issue 1 Part 2 (149), 2019 year, 102-105 pages, index UDK 616.62-003.7-07-08