Pantus A. V., Rozhko M. M., Kovalchuk N. E., Yarmoshuk I. R., Grekulyak V. V


About the author:

Pantus A. V., Rozhko M. M., Kovalchuk N. E., Yarmoshuk I. R., Grekulyak V. V



Type of article:

Scentific article


The task of periodontal therapy is to implement primary and secondary prophylaxis of periodontal diseases by controlling the factors of inflammation and maintenance and improving the condition and function of the gums, periodontal ligament, cement of the root and surrounding bones, which in the complex form the structure of the periodontal tooth. Objective. Determine the level of effectiveness and justify the feasibility of using a fibrous matrix of polylactic acid foams as an alternative approach to directed bone regeneration during the reconstruction of intraosseal periodontal defects of the jaws. Object and methods. In order to achieve this goal, the study process was divided into two interrelated stages. A complex of diagnostic (cone-ray computer research, probing, instrumental and biochemical diagnostics) and surgical manipulations was performed for the purpose of restoration of intraosse jaundice defects and control over the results of treatment. Using the randomized distribution method, the total study population was divided into the main group (29 persons – Group I) and the comparison group (27 persons – Group II). Results. In determining the level of reduction of bone defect volume in 12 months after surgery, using the data of cone-ray computer tomography and the graphic principle of superimposition, it was possible to establish that in the I group the volume of bone defect decreased by 31,19±4,07 conditional units, and in the second group – by 29.18±1.39 units. The obtained results indicate that the use of a fibrous matrix of polylactic acid foams may serve as an effective alternative for the treatment of intraosse periodontal defects in the jaws during the implementation of the directed bone regeneration procedure. Advantages of a fibrous matrix, as well as a bone substitute of xenogeneic origin, consist in the access to virtually unlimited volume of material necessary to replace the periodontal defect, eliminate the need for autologous bone tissue, reduce the level of discomfort in the patient during surgical intervention and optimize the surgical manipulation algorithm directed on the restoration of bone deficiency in the area of the periodontal affected units of the dentition. Conclusion. The implementation of the directed bone regeneration procedure with the use as the main material for filling intraosseous defects of the jaw of the fibrous matrix of polylactic acid foams is an effective alternative to the classical approaches to the surgical treatment of two- and three-wall periodontal lesions


periodontitis, fibrous matrix, polylactic acid.


  1. Haffajee AD, Socransky SS, Gunsolley JC. Systemic anti‐infective periodontal therapy. A systematic review. Annals of Periodontology. 2003;8(1):115-81.
  2. Heitz Mayfield LA, Lang NP. Surgical and nonsurgical periodontal therapy. Learned and un learned concepts. Periodontology. 2013;62(1): 218-31.
  3. Jeffcoat MK. Impact of periodontal therapy on general health: evidence from insurance data for five systemic conditions. American journal of preventive medicine. 2014;47(2):166-74.
  4. Graziani F. Systemic inflammation following non surgical and surgical periodontal therapy. Journal of clinical periodontology. 2010;37(9): 848-54.
  5.  Kao RT, Nares S, Reynolds MA. Periodontal regeneration – intra bony defects: a systematic review from the AAP regeneration work shop. Journal of periodontology. 2015;86:77-104.
  6. Chambrone L. Evidence based periodontal plastic surgery: an assessment of quality of systematic reviews in the treatment of recession type defects. Journal of Clinical Periodontology. 2010;37(12):1110-8.
  7. Braun X. Diagnostic accuracy of CBCT for periodontal lesions. Clinical oral investigations. 2014;18(4):1229-36.
  8. Comaneanu RM. Virtual 3D reconstruction, diagnosis and surgical planning with Mimics software. International Journal of Nano and Biomaterials. 2012;4(1):69.
  9. Dellavia C. A new method to evaluate volumetric changes in sinus augmentation procedure. Clinical implant dentistry and related research. 2014;16(5):684-90.
  10. Jermyn M. Fast segmentation and high-quality three-dimensional volume mesh creation from medical images for diffuse optical tomography. Journal of biomedical optics. 2013;18(8):086007.
  11. Goncharuk-Khomyn M, Andrii K. Evaluation of Peri-Implant Bone Reduction Levels from Super imposition Perspective: Pilot Study among Ukrainian Implantology Practice. Pesquisa Brasileiraem Odontopediatria e Clinica Integrada. 2018;18(1):38-56.
  12. Srivastava N, Nayak PA, Rana S. Point of Care-A Novel Approach to Periodontal Diagnosis-A Review. Journal of clinical and diagnostic research: JCDR. 2017;11(8):122-6.
  13. Highfield J. Diagnosis and classification of periodontal disease. Australian dental journal. 2009;54:11-26.

Publication of the article:

«Bulletin of problems biology and medicine» Issue 2 Part 1 (150), 2019 year, 320-324 pages, index UDK 616-003.93+616.314.-089+616.314.17-008.1