CLINICAL AND LABORATORY SUBSTANTIATION OF THE PRINCIPLES OF PREVENTION AND TREATMENT OF INFLAMMATORY PERIODONTAL DISEASES
About the author:
Sadigova N. N.
Type of article:
Purpose. Improving the effectiveness of complex treatment and prevention of primary forms of inflammatory periodontal diseases. Methods. Patients with chronic generalized mild periodontitis were divided into 3 groups: basic, comparison and control – (12 people). The comparison group (13 people) received treatment with the appointment of toothpaste Curasept ADS and the main group (13 people) treatment, as in the previous group, but with the additional appointment of synbiotic Maxilac. Results. Hygiene index after treatment decreased in all groups. But the therapeutic measures carried out in the main group were accompanied by a more pronounced decrease in the values of the PHP index at all stages of observation. The group, which used a synbiotic achieved positive dynamics of hygienic index was more stand – 1,14 ± 0,053; 1,27 ± 0,044 and 1.82 ± 0,052, value, index, PHP, respectively, in the intervention group, comparison group and control group at the final stage of the research (p<0.001). The expressed action of synbiotic on growth and activity of microorganisms of oral fluid is established. The best results were observed in the dynamics of reducing the content of periodontal microflora A. actinomycetemcomitans, P. gingivalis and P. intermedia in the oral cavity in patients of the main group. So, if the value of A. actinomycetemcomitans after treatment in the main group was 0.47 ± 0.057 points, in the comparison group at the same time the index was higher and amounted to 0.59 ± 0.145 points, and in the control group the index values were even higher and reached a maximum value of 0.67 ± 0.045 points (p<0.05). Conclusion. The introduction of synbiotic increased the effectiveness of treatment of inflammatory periodontal diseases against the background of improving the hygienic state of the oral cavity and reducing bacterial load in patients, including significant elimination of aggressive periodontal pathogenic species of oral microflora.
periodontitis, indexes, symbiotics, treatment.
- Bergstrom J. Smoking rate and periodontal disease prevalence: 40-year trends in Sweden, 1970-2010. J Clin Periodontol. 2014;41:952-7.
- Hosseinpoor AR, Itani L, Petersen PE. Socio-economic inequality in oral healthcare coverage: results from the World Health Survey. J Dent Res. 2012;91(3):275-81.
- Nascimento GG, Leite FR, Do LG, Peres KG, Correa MB, Demarco FF, et al. Is weight gain associated with the incidence of periodontitis? A systematic review and meta-analysis. J Clin Periodontol. 2015;42:495-505.
- O’Mullane DM, Baez RJ, Jones S, Lennon MA, Petersen PE, Rugg-Gunn AJ, et al. Fluoride and Oral Health. Community Dent Health. 2016;33(2):69-99.
- Raitapuro-Murray T, Molleson TI, Hughes FJ. The prevalence of periodontal disease in a Romano-British population c 200-400 AD. Br Dent J. 2014;217:459-66.
- Watt RG, Heilmann A, Listl S, Peres MA. London Charter on Oral Health Inequalities. J Dent Res. 2016;95(3):245-7.
- World Health Organization. Universal Health Coverage, Fact sheet. Published 2018. Accessed 7 May, 2018.
- Dosseva-Panova VT, Popova CL, Panov VE. Subgingival microbial profile and production of proinflammatory cytokines in chronic periodontitis. Folia Med. (Plovdiv). 2014;56(3):152-60.
- Kinney JS, Morelli T, Oh M, Braun TM, Ramseier CA, Sugai JV, Giannobile WV. Crevicular fluid biomarkers and periodontal disease progression. J. Clin. Periodontol. 2014;41(2):113-20.
- de Freitas CV, Galdez LP, Dias HL, Cirelli JA, Souza EM, da Silva VC. Effect of Subgingival Irrigation with Different Substances in the Treatment of Periodontal Disease. A Histometric Study in Rats. J Int Acad Periodontol. 2016 Jan 14;18(1):2-6.
- Marsh PD. Contemporary perspective on plaque control. British Dental Journal. 2012;212:601-6. 12. Schonfeld SE. Strategies for managing periodontal inflammation. J. Calif. Dent. Assoc. 2010;38(4):272-83.
Publication of the article:
«Bulletin of problems biology and medicine» Issue 4 Part 1 (153), 2019 year, 342-347 pages, index UDK 616.31-08-039.71.004.64