ASSOCIATION BETWEEN CHANGES IN THE PSYCHOLOGICAL STATUS AND METABOLIC DISORDERS IN WOMEN WITH ARTERIAL HYPERTENSION, OBESITY AND LEFT VENTRICULAR DIASTOLIC DYSFUNCTION

Kyrychenko N. M.

CLINICAL AND EXPERIMENTAL MEDICINE

Scentific article

Type 2 diabetes is one of the most common chronic non-infectious disease. Studies have shown that gender is closely associated with the onset of symptoms of anxiety and depression. Moreover, in women, psychological status disorders are observed on average three times more often, however, the mechanisms of these associations are still not fully understood. The aim was to study the psychological status of women with hypertension, obesity and left ventricular diastolic dysfunction with varying degrees of metabolic disorders. Object and methods. 125 patients aged 40-60 years with hypertension and LVDD were examined. The patients cohort of 100 people was divided into groups depending on BMI and the presence of diabetes. Groups 1, 2 and 3 consisted of patients without diabetes with degrees of obesity I, II and III, respectively. Group 4 included patients with varying degrees of obesity and concomitant diabetes. Another 25 patients with normal BMI without diabetes made up the control group. To assess the psychological status, the scales of Beck’s depression and SpielbergerHanin’s anxiety were used. Questionnaire results were interpreted according to recommendations. Statistical data processing was performed using the Statistica for Windows Version 6.0 software package. Results. An increase in the level of reactive and personal anxiety, as well as the number of points on the SDB, depending on the increase in BMI, was established. According to the results of the Beck questionnaire, no patient was found in the comparison groups who scored more than 19 points (significant depression). In the group with concomitant diabetes there was a 1.2-fold increase in the number of patients who scored from 10 to 18 points. Women with diabetes showed an increase in the number of patients with a moderate degree of personal anxiety by 1.2 times compared with the group without diabetes. Patients who scored from 31 to 45 points (moderate) for SRA in the group with diabetes were 1.5 times more than in group without concomitant diabetes, an increase in the number of patients with a high degree of reactive anxiety in the group with concomitant diabetes was also compared with people without diabetes 1.3 times. Conclusions. Women with hypertension, obesity, and diastolyc dysfunction are characterized by increased levels of reactive and personal anxiety, as well as an increase in the number of points by Beck depression scale, the degree of which increases with increasing metabolic disorders. In women with hypertension, obesity, and LVDD, the presence of type 2 diabetes is associated with an increase in the frequency of moderate and high anxiety and an increased number of points on the Beck depression scale compared with patients who do not have concomitant diabetes

psychological status, diabetes, women, obesity, anxiety.

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«Bulletin of problems biology and medicine» Issue 4 Part 2 (154), 2019 year, 102-107 pages, index UDK 616.12-008.331.1+613.25+616.122-008.6]-008.9:159.942.53-055.2

10.29254/2077-4214-2019-4-2-154-102-107